"For one of our products, the data on CEP holders which we could not extract from other sources was easily retrieved from SmartChem knowledgebase which helped the organization to take quick and correct business decision."

- Sourcing Manager, one of the top Pharmaceutical companies, Europe

"The three-molecule trial was a success. As a matter of fact, we are practicing some of the chemistry from two of the trial RouteDesigns in our laboratories today.”

- Head Science and Technology at a leading chemical company, USA.

Welcome to CI2E Quarterly – Issue 3,
September 2009!

CI2E Quarterly is celebrating its 5^th year of connecting with R&D, Sourcing and Business Development professionals from Life sciences and Chemical industry worldwide. In the 5 years span, CI2E family has grown to over 5000 readers from 900 plus companies spanning across 25 countries around the globe. As a part of the celebration, we invite our readers to participate in exciting CI2E contests and avail special discount offers on "My Forum" and "Sponsor" sections.

• ROW2 World: Announcement of “My Dream Knowledgebase” contest and updates on ROW2 & its offerings

• Article: Impact of the recessionary environment on the Biotech and Life Sciences Industry in Europe

• Picks of the Quarter: Links to various interesting articles

• My Forum: Annemieke Timmers, CPhI Worldwide and Lauren Lamoureux, ACS ProSpectives talk about their upcoming events

• Entertainment: Interesting Environment facts!

ROW2 World :

ROW2 News

SmartChem further enREACHed: SmartChem is the only knowledgebase, which keeps its users up-to-date on REACH related key information thus helping them deal with REACH challenges. Realizing the implications and importance of REACH legislation to the Chemical and Life Sciences industry, SmartChem has been enriched with REACH Corner. SmartChem users use it as a “ready reckoner” for details on REACH Pre-registered, High Concern and Prioritized substances. In addition, users can also check the Pre-registration status for SmartChem chemicals. Read more on REACH enrichments below.

“My Dream Knowledgebase” Contest: A knowledgebase forms a very critical resource while performing day-to-day activities such as identifying raw materials sources, identifying credential suppliers, Business Development opportunities, outsourcing partners and many more…
Considering that you also must be referring to some of the available knowledgebases daily, are you fully satisfied with your current knowledgebases?

• What is your Dream Knowledgebase?
• What will make your knowledgebase complete?
• Which more additions you wish to see in it to make it your perfect assistant for handling day-to-day challenges efficiently?

With the CI2E’s ongoing 5th year celebrations, ROW2 announces
“My Dream Knowledgebase” contest!
To participate, you need to pen down your thoughts on the above-mentioned questions in just 100 words and email them to us here.

The Top 5 “My Dream Knowledgebase” ideas will win* exciting prizes. First 2 completed entries received here, will win “Fastest Two” prizes. Hurry! Do not miss your chance to win exciting prizes...

*ROW2 will solely decide eligibility of entries and winners.

Upcoming Events: ROW2 will be visiting CPhI Worldwide, CPhI India and ACS ProSpectives Conference on Process Chemistry in the Pharmaceutical Industry.

SmartChem News

Latest Enhancements: Recently, SmartChem was enhanced with REACH Corner, Details on REACH Pre-registered Chemicals and Alerts on REACH Prioritized Substances.

• REACH Corner - Acts as a ready reckoner for all REACH related key information.

• Details on REACH Pre-registered Chemicals - Users can view details on over 140,000 REACH Pre-registered chemicals and also learn about Pre-registration status for SmartChem Chemicals.

• Alerts on REACH Prioritized Substances - 7 REACH High Concern Chemicals have been Prioritized by ECHA for Authorization. SmartChem alerts its users towards consumption of these chemicals.

We thank all our SmartChem users for their encouraging feedback on the REACH corner enrichment. To know more about this enrichment, click here.

RouteDesign News

Celebrations and Jubilations: Its time now for celebrations! ROW2 will be celebrating Process Research Chemists Day on November 10, 2009 and Thanksgiving Day on November 26, 2009 with its customers for the 4th consecutive year.

Important Events: October’09 to December’09

October:
13-14 : Synthetic Heterocyclic Chemistry (Event Postponed)
13-15 : CPhI Worldwide: Madrid, Spain

November:
02-04 : BIO Europe 2009: Vienna, Austria
02-04 : ACS ProS: Process Chemistry in the Pharma Industry:
Durham, NC

December:
01-03 : CPhI India: Mumbai, India
03-04 : New Horizons in Catalysis: Cologne, Germany
07-08 : Chemspec Middle East: Dubai (Postponed till
           November 29-30, 2010)

Featured Article

From the point of view of the European biotech and life sciences sector, the current economic situation has just added to the problems that it already faced. The pharma sector has been under pressure from governments to reduce the costs of prescription drugs while at the same time pharmaceutical majors have been experiencing shrinking pipelines.

A look at the financial performance of European pharma majors demonstrates the overall effect of these pressures and the impact of the recession. While sales have increased through the first half of 2009 for most, income is generally down. Swiss healthcare major Roche, for example, saw its first half sales rise by 5% to CHF24bn, but net income dropped 29% to CHF4bn. In terms of its pharmaceutical sales, the company reported a sales growth of 11%, twice the global market rate; however, a good proportion of this increase was due to sales of Tamiflu, boosted by the threat of an H1N1 virus pandemic.

To read the full article click here.

Interesting Links

The Pharmerging Future
Published in PharmExec.com: Jul’ 09 issue

An enlightening article on how some of the select emerging Pharma markets are eclipsing the once major Pharma Markets and contributing to the 2009’s global growth.

So Much for Summer Slump: July Financings Keep Pace
Published in BioWorld Today: Aug’09 issue

Good news for biotech industry! Inspite of the global economic downturn, biotech industry with the help of public company financings, outpaced the last year’s financial drawings. Read the article to know the details.

Ensuring Product Quality and Managing Risk: Validate, Verify, Implement
Published in BioPharm.com: Jul’09 issue

An informative article on some very essential procedures, which should be followed by the Biopharmaceutical companies to manage their supply chains efficiently.

Featured Article Cont'd.

Pharma majors have been looking to the biotech sector to fill those pipeline gaps through collaborations, or increasingly through acquisition of those collaborative partners. Roche’s takeover of Genentech earlier this year is perhaps the most high profile example.

Many pharma companies have been able to take advantage of the shortage of capital available to smaller biotech firms as a result of the severe cutbacks in the availability of credit from the major banks and venture capitalists. One US biotech observer said that many biotech firms had just a few months left of financing and in recent months there has been news of increasing numbers of those biotechs seeking a ‘white knight’ to purchase them or at least some of their intellectual property to keep them in business.

European pharma companies are also watching moves by Japanese competitors to partner with Indian companies, particularly as regards the development of generic pharmaceuticals, encouraged by the Japanese government’s moves to follow other developed nations in supporting the substitution of generics for branded prescription drugs. Currently generics account for around 5% of the Japanese market, worth around $3bn, but the government is hoping this penetration will increase to 30% by 2012/13.

For companies in the crop protection sector, there are different pressures that include the increasing resistance of pests to current products and burgeoning regulations, particularly within Europe that is limiting the range of products that can be used, while at the same time, there is an increasing pressure to feed an ever-growing global population and concerns about food security. According to the UN Food and Agriculture Organization, agricultural output will have to double by 2050 to meet the needs of a global population that is forecast to reach over 9bn and to counter the problem of only the same, or possibly even less, land area currently under cultivation being available for food production by that time.

Three of the six major agrochemical companies are located in Europe and they are all confident that technology will meet this challenge. Indeed one former R&D director from one of the Big Three believes that if today’s best farming practices were adopted across the world then it should be possible to produce triple the amount of food.

There is also a consensus that the sector will have to continue product development across all three of the current approaches to pest management: conventional chemical, biotech and biocontrol. However, there are concerns that investment in plant science and agricultural development in general has fallen behind. Cooperation between farmers, crop protection developers, plant breeders and governments at all levels will be needed in the future.

About the author:

Neil Eisberg, a graduate from the University of Sussex with an honours degree in Organic Chemistry, is the Editor of Society of Chemical Industry’s fortnightly publication, Chemistry & Industry. Chemistry & Industry is the leading independent chemistry-based publication bridging the gap between scientific research and industrial applications. Prior to Chemistry & Industry, Neil was the Head of Media Relations at the Chemical Industries Association (CIA). In his over 25 years of career, he has been associated with a number of esteemed publishing houses such as Manufacturing Chemist, Reed Business Information and CIA.

Contact: Neil Eisberg
neil.eisberg@tenalpspublishing.com

To sponsor future newsletters, write to us here.

Ms. Annemieke Timmers, Event Director at UBM International Media talks about CPhI Worldwide 2009

CPhI Worldwide’s continuous growth over the years has made the event the most important on the pharmaceutical calendar. Join the CEOs and Business Development Managers from over 125 countries as they gather in Madrid to discuss the industry’s most important trends, developments and innovations. For your free ticket, please click here.

Lauren Lamoureux, Senior Marketing Associate, ACS gives an insight to the ACS ProSpectives Conferences

ACS ProSpectives Conferences are designed for industry scientists, emphasizing ideas immediately applicable to your work. These conferences feature a balanced combination of speakers from academia and industry, and the ideas presented can save your company huge amounts of research time and dollars and provide you with guaranteed great networking opportunities.

Interesting Environment facts:

Answers to former Fun Trivia:

Issue 1 :
Switching the first letter to the end of each word gives the same word when reading it backwards.
Issue 2 :
Alternate vowels and consonants.